Le Bouëdec G, Curé H, de Latour M, Dauplat J
Service de chirurgie, centre Jean-Perrin, centre de lutte contre le cancer, 58, rue Montalembert, B.P. 392, 63011 Clermont-Ferrand, France.
Rev Med Interne. 2001 Aug;22(8):753-7. doi: 10.1016/s0248-8663(01)00422-2.
Stewart-Treves syndrome has been defined by the eponymous authors as a lymphangiosarcoma in a setting of postmastectomy upper extremity lymphoedema.
The clinical record of one patient with Stewart-Treves syndrome is analyzed. The primary angiosarcoma of the skin represented by a purple nodule occurred on a chronic lymphoedematous arm following radical mastectomy and axillary lymph node dissection for breast carcinoma performed 9 years earlier. Immunohistochemistry tests formally eliminated epithelial cutaneous metastasis and produced evidence in favour of conjunctive vascular tissue origin of the tumor.
Conservative surgery for breast cancer, application of axillary sentinel node biopsy in the lymphatic staging and prevention of arm lymphoedema should reduce the incidence of this syndrome.
斯图尔特 - 特里夫斯综合征被其同名作者定义为乳房切除术后上肢淋巴水肿情况下发生的淋巴管肉瘤。
分析了1例斯图尔特 - 特里夫斯综合征患者的临床记录。以紫色结节为表现的皮肤原发性血管肉瘤发生在9年前因乳腺癌行根治性乳房切除术和腋窝淋巴结清扫术后的慢性淋巴水肿手臂上。免疫组织化学检测正式排除了皮肤上皮转移，并提供了支持肿瘤起源于结缔组织血管的证据。
乳腺癌的保守手术、腋窝前哨淋巴结活检在淋巴分期中的应用以及手臂淋巴水肿的预防应可降低该综合征的发病率。
