Lindsay D S, Ritter D M, Brake D
Center for Molecular Medicine and Infectious Diseases, Department of Biomedical Sciences and Pathobiology, Virginia-Maryland Regional College of Veterinary Medicine, Virginia Tech, Blacksburg 24061-0342, USA.
J Parasitol. 2001 Aug;87(4):909-11. doi: 10.1645/0022-3395(2001)087[0909:OEIDFM]2.0.CO;2.
Neospora caninum is an apicomplexan parasite that causes neonatal neuromuscular disease in dogs and abortions in cattle. Bovine neosporosis is a major production problem worldwide. The parasite is transmitted to cattle via oocysts excreted by dogs or by transplacental transmission. Dogs are the only proven definitive host for N. caninum. One of 3 dogs fed mouse brains containing tissue cysts of a wild-type N. caninum strain CK0160SC3B (CKO) excreted oocysts in its feces. Two of 3 dogs fed mouse brains containing tissue cysts from a cloned line of the CKO strain excreted N. caninum oocysts in their feces. The results indicate that a single N. caninum tachyzoite contains all the genetic information needed to produce the asexual and sexual cycles in the canine intestine.
犬新孢子虫是一种顶复门寄生虫，可导致犬的新生儿神经肌肉疾病和牛的流产。牛新孢子虫病是全球主要的生产问题。该寄生虫通过犬排出的卵囊或经胎盘传播感染牛。犬是唯一经证实的犬新孢子虫终末宿主。3只喂食含有野生型犬新孢子虫菌株CK0160SC3B（CKO）组织包囊的鼠脑的犬中有1只在粪便中排出了卵囊。3只喂食含有CKO菌株克隆系组织包囊的鼠脑的犬中有2只在粪便中排出了犬新孢子虫卵囊。结果表明，单个犬新孢子虫速殖子包含在犬肠道中产生无性和有性周期所需的所有遗传信息。
