克罗恩病回肠肛管吻合口处腺癌：一例报告
Adenocarcinoma at the site of ileoanal anastomosis in Crohn's disease: report of a case.
作者信息
Kotanagi H, Kon H, Iida M, Ito M, Koyama K
机构信息
Department of Surgery, Akita University School of Medicine, 1-1-1 Hondo, Akita 010-8543, Japan.
出版信息
Dis Colon Rectum. 2001 Aug;44(8):1210-3. doi: 10.1007/BF02234646.
PURPOSE
Proctocolectomy with ileoanal anastomosis has gained acceptance for the treatment of patients with ulcerative colitis. However, there are some patients with Crohn's disease who received ileoanal anastomosis, because some Crohn's colitis is difficult to differentiate from ulcerative colitis. The risk of cancer development at the site of ileoanal anastomosis has not been emphasized in Crohn's disease.
METHODS
A 12-year-old patient with Crohn's disease was treated by proctocolectomy with straight ileoanal anastomosis. Twenty-five years after the operation, the patient noticed the tumor that developed at the site of ileoanal anastomosis.
RESULTS
This article presents a patient with Crohn's disease who developed invasive adenocarcinoma at the site of ileoanal anastomosis 25 years after proctocolectomy with ileoanal anastomosis.
CONCLUSIONS
An ileoanal anastomosis does not eliminate the risk of cancer development, and surveillance after this operation seems advisable.
目的
回肠肛管吻合术式的全结直肠切除术已被广泛用于治疗溃疡性结肠炎患者。然而，有一些克罗恩病患者也接受了回肠肛管吻合术，因为部分克罗恩结肠炎难以与溃疡性结肠炎相鉴别。克罗恩病患者回肠肛管吻合部位发生癌变的风险尚未得到重视。
方法
一名12岁的克罗恩病患者接受了全结直肠切除及直型回肠肛管吻合术治疗。术后25年，患者发现回肠肛管吻合部位出现肿瘤。
结果
本文报告了一名克罗恩病患者，在接受回肠肛管吻合术式的全结直肠切除术后25年，回肠肛管吻合部位发生了浸润性腺癌。
结论
回肠肛管吻合术并不能消除癌变风险，术后进行监测似乎是可取的。
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