Urbanski P P
Herz- und Gefäss-Klinik, Bad Neustadt, Germany.
Med Sci Monit. 2001 Sep-Oct;7(5):899-902.
Conduits with biological valves are rarely used for aortic root replacement because of technical problems when degeneration of the valve prosthesis requires reoperation. A composite graft as described could likely avoid this problem.
Between November 1998 and November 1999, 28 consecutive patients underwent replacement of the ascending aorta and aortic valve with a stentless valved composite graft. The indication for surgery was aneurysm of the ascending aorta (26 patients) and aortic dissection (2 patients). The composite graft was assembled during surgery using a stentless porcine aortic bioprosthesis (Toronto SPV) and a woven polyester collagen-coated vascular prosthesis (InterGard).
There was no hospital mortality. Echocardiographic evaluation before discharge showed excellent hemodynamics with a mean transvalvular gradient of 8.5 mmHg (standard deviation I3.0 mmHg) and no regurgitation across the valve. Within a follow-up period of up to one year there was one late death because of a cerebral hemorrhage under anticoagulation.
The valved composite graft described offers the excellent hemodynamic performance of a stentless biological valve and is expected to avoid major technical difficulties should later replacement of the biological prosthesis due to structural failure become necessary, because only the valve cusps need to be resected, leaving the tube graft untouched.
由于生物瓣膜假体退变需要再次手术时存在技术问题,带生物瓣膜的管道很少用于主动脉根部置换。所述的复合移植物可能会避免这个问题。
1998年11月至1999年11月,连续28例患者接受了无支架带瓣复合移植物置换升主动脉和主动脉瓣。手术指征为升主动脉瘤(26例)和主动脉夹层(2例)。复合移植物在手术过程中使用无支架猪主动脉生物假体(多伦多SPV)和编织聚酯胶原涂层血管假体(InterGard)组装而成。
无住院死亡病例。出院前的超声心动图评估显示血流动力学极佳,平均跨瓣压差为8.5 mmHg(标准差3.0 mmHg),瓣膜无反流。在长达一年的随访期内,有1例因抗凝治疗下脑出血导致的晚期死亡。
所述带瓣复合移植物具有无支架生物瓣膜出色的血流动力学性能,并且预计在因结构故障需要后期更换生物假体时可避免重大技术困难,因为仅需切除瓣膜叶尖,而不触动人工血管。