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巴西东南部儿童中由A组和B组呼吸道合胞病毒引起的感染的发生率和严重程度

Occurrence and severity of infections caused by subgroup A and B respiratory syncytial virus in children in southeast Brazil.

作者信息

Cintra O A, Owa M A, Machado A A, Cervi M C, Figueiredo L T, Rocha G M, Siqueira M M, Arruda E

机构信息

Department of Pediatrics, University of São Paulo School of Medicine at Ribeirão Preto, Ribeirão Preto, São Paulo, Brazil.

出版信息

J Med Virol. 2001 Oct;65(2):408-12. doi: 10.1002/jmv.2049.

DOI:10.1002/jmv.2049
PMID:11536252
Abstract

The frequency and severity of infections caused by respiratory syncytial virus (RSV) were assessed in children <2 years of age seen at the emergency department. The frequency of RSV detection in the clinical virology laboratory during the past 3 years was also analyzed retrospectively. RSV was found in 21.6% (188/869) of the samples collected from children seen at the emergency department and was found to be more frequent during the autumn, being less frequent or negligible by midwinter. RSV subgroups A and B co-circulated within the same time period in children seen at the emergency department, with varying predominance of either subgroup. There was no significant association of RSV subgroup with disease severity, but only a trend for RSV subgroup B being more frequent in children with risk factors for severe disease.

摘要

对在急诊科就诊的2岁以下儿童中由呼吸道合胞病毒(RSV)引起的感染频率和严重程度进行了评估。还回顾性分析了过去3年临床病毒学实验室中RSV的检测频率。在从急诊科就诊儿童中采集的样本中,21.6%(188/869)检测到RSV,且在秋季更为常见,到冬季中期则频率降低或可忽略不计。在急诊科就诊的儿童中,RSV A组和B组在同一时期共同流行,两组的优势程度有所不同。RSV亚组与疾病严重程度之间无显著关联,但仅有一种趋势,即RSV B组在有严重疾病危险因素的儿童中更为常见。

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