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Glucocorticoid effects on immune cell activation by staphylococcal exotoxins and lipopolysaccharide.

作者信息

Chapes S K, Kopydlowski K M, Fleming S D, Iandolo J J

机构信息

Division of Biology and Department of Pathology, Kansas State University, Manhattan, USA.

出版信息

Trans Kans Acad Sci. 1992;95(1-2):23-8.

PMID:11537979
Abstract

Experiments were conducted to determine the effects of physiologically elevated corticosterone on the activation of macrophages and T cells. These studies find that the elevation of corticosterone does not affect the expression of membrane receptors on macrophages and does not affect the activation of macrophages to produce cytokines. In contrast, elevated corticosterone levels correlate with enhanced T cell proliferation to both mitogens and superantigens.

摘要

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