LeBlanc A D, Jaweed M, Evans H
Baylor College of Medicine, Houston, Texas, USA.
Clin J Sport Med. 1993 Jan;3(1):26-30. doi: 10.1097/00042752-199301000-00006.
The objective of this study was to investigate spin echo T2 relaxation time changes in thigh muscles after intense eccentric exercise in healthy men. Spin echo and calculated T2 relaxation time images of the thighs were obtained on several occasions after exercise of one limb; the contralateral limb served as control. Muscle damage was verified by elevated levels of serum creatine kinase (CK). Thirty percent of the time no exercise effect was discernible on the magnetic resonance (MR) images. In all positive MR images (70%) the semitendinosus muscle was positive, while the biceps femoris, short head, and gracilis muscles were also positive in 50% and 25% of the total cases, respectively. The peak T2 relaxation time and serum CK were correlated (r = 0.94, p<0.01); temporal changes in muscle T2 relaxation time and serum CK were similar, although T2 relaxation time remained positive after serum CK returned to background levels. We conclude that magnetic resonance imaging can serve as a useful tool in the evaluation of eccentric exercise muscle damage by providing a quantitative indicator of damage and its resolution as well as the specific areas and muscles.
本研究的目的是调查健康男性在进行高强度离心运动后大腿肌肉自旋回波T2弛豫时间的变化。在一侧肢体运动后的多个时间点获取大腿的自旋回波和计算得到的T2弛豫时间图像；对侧肢体作为对照。通过血清肌酸激酶（CK）水平升高来证实肌肉损伤。在30%的时间里，磁共振（MR）图像上未发现运动效应。在所有阳性MR图像（70%）中，半腱肌呈阳性，而股二头肌短头和股薄肌分别在50%和25%的总病例中呈阳性。T2弛豫时间峰值与血清CK相关（r = 0.94，p<0.01）；肌肉T2弛豫时间和血清CK的时间变化相似，尽管在血清CK恢复到背景水平后T2弛豫时间仍为阳性。我们得出结论，磁共振成像可作为评估离心运动肌肉损伤的有用工具，通过提供损伤及其恢复的定量指标以及特定区域和肌肉的信息。
