Ma J, Zhang L F, Yu Z B, Zhang L N
Department of Aerospace Physiology, Fourth Military Medical University, Xi'an, P.R. China.
J Gravit Physiol. 1997 Jul;4(2):P45-6.
Recent works have shown that postflight orthostatic intolerance involves multiple alterations in physiological function during actual or simulated microgravity. In our previous work, we demonstrated that 14-day tail-suspension resulted in an impaired ability of vascular smooth muscle to develop tension in arteries confined to the hindquarter, which have been suggested as an important factor accounting for the occurrence of orthostatic intolerance. To our knowledge, data on arterial vasoreactivity alterations induced by simulated microgravity longer than two weeks are not found. The aim of the present work was to characterize the time course of alterations in vasoconstrictor properties of hindquarter arteries during tail-suspension up to eight weeks, and to examine whether these alterations are reversible.
最近的研究表明，飞行后体位性不耐受涉及实际或模拟微重力期间生理功能的多种改变。在我们之前的研究中，我们证明，14天的尾部悬吊导致后肢动脉血管平滑肌产生张力的能力受损，这被认为是体位性不耐受发生的一个重要因素。据我们所知，尚未发现关于模拟微重力诱导超过两周的动脉血管反应性改变的数据。本研究的目的是描述长达八周的尾部悬吊期间后肢动脉血管收缩特性改变的时间进程，并研究这些改变是否可逆。
