质子放射生物学与不确定性

Proton radiobiology and uncertainties.

作者信息

Yang T C

机构信息

NASA Johnson Space Center, Houston, TX 77058, USA.

出版信息

Radiat Meas. 1999 Jun;30(3):383-92. doi: 10.1016/s1350-4487(99)00209-7.

DOI:10.1016/s1350-4487(99)00209-7

PMID:11543142

Abstract

This paper briefly reviews proton radiobiology. Clinical applications of protons produced by accelerators have led to a significant biological literature that contributes to our goal of estimating the proton shielding requirements for human interplanetary missions. Protons are primarily a low-LET radiation with biological effects much like gamma radiation. There are however data indicating enhanced biological effectiveness for small doses of very low energy (<10 MeV) stopping protons, and some limited data for extremely high energy protons (>0.5 GeV).

摘要

本文简要回顾了质子放射生物学。加速器产生的质子的临床应用已催生了大量生物学文献，有助于我们实现估算人类星际任务中质子屏蔽要求的目标。质子主要是一种低传能线密度辐射，其生物学效应与伽马辐射非常相似。然而，有数据表明，小剂量极低能量（<10兆电子伏）的终止质子具有更高的生物学效能，还有一些关于极高能量质子（>0.5吉电子伏）的有限数据。