Harper J F
Dept of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037, USA.
Trends Plant Sci. 2001 Sep;6(9):395-7. doi: 10.1016/s1360-1385(01)02023-4.
To understand Ca2+ signaling, we need to identify all the Ca2+ transporters and their regulatory components. The first Ca2+ transporters to be cloned from plants and shown to have regulated activity were calmodulin-dependent Ca2+ -pumps. The regulation of these pumps suggests that being able to change the rate of Ca2+ efflux is important for Ca2+ signaling. The identification of pumps and antiporters in different subcellular locations is helping to dissect the complexities of Ca2+ signaling in plants.
为了理解钙离子信号传导，我们需要识别所有的钙离子转运体及其调节成分。最早从植物中克隆出来并显示具有调节活性的钙离子转运体是钙调蛋白依赖性钙离子泵。这些泵的调节表明，能够改变钙离子外流速率对钙离子信号传导很重要。在不同亚细胞位置识别泵和反向转运体有助于剖析植物中钙离子信号传导的复杂性。
