大肠杆菌的磷酸盐结合蛋白对于磷酸调节子受P(i)调控的表达并非必不可少。
The phosphate-binding protein of Escherichia coli is not essential for P(i)-regulated expression of the pho regulon.
作者信息
Hoffer S M, Tommassen J
机构信息
Department of Molecular Microbiology and Institute of Biomembranes, Utrecht University, 3584 CH Utrecht, The Netherlands.
出版信息
J Bacteriol. 2001 Oct;183(19):5768-71. doi: 10.1128/JB.183.19.5768-5771.2001.
Abstract
Disruption of pstS encoding the P(i)-binding protein in Escherichia coli generally leads to the constitutive expression of the pho regulon. We demonstrate that P(i)-controlled expression is restored when the activity of the P(i) transporter PitA or PitB is increased. Apparently, PstS is not an essential component of the signal transduction pathway.
摘要
编码大肠杆菌中与无机磷酸（P(i)）结合蛋白的pstS基因的破坏通常会导致pho调节子的组成型表达。我们证明，当P(i)转运蛋白PitA或PitB的活性增加时，P(i)控制的表达得以恢复。显然，PstS不是信号转导途径的必需成分。
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