Poltorakov A P
N. N. Semenov Institute of Chemical Physics, Russian Academy of Science, Kosygin str. 4, Moscow 117977, Russia.
Zh Obshch Biol. 2001 Mar-Apr;62(2):110-31.
We have continued an analysis of survival curves by the model of the vital receptors (MVR). The main types survival function (E-, TW- and GM-distributions) have been considered. It was found that the maximal life span depends on the threshold concentration of vital receptors. Equations are obtained for the dependence of the maximal life span on the kinetic parameters in the reactions of inactivation, destruction and inactivation. Dependence of maximal time life on initial size of the population have been considered. The influence of temperature on the survival curves is analysed by E-distribution. Equations are founded for the description of thermosurvival and thermoinactivation curves. Equation are obtained for the dependence of density function and it characteristics (modal and antimodal age, coefficient of asymmetry) on the MVR parameters. It was shown that E-, TW- and GM-distribution has different types of asymmetry. The coefficient of asymmetry of GM-distribution is associated on the MVR parameters. It is assumed that symmetry of the curves of mortality and birth-rate is coordinated by the mechanisms of MVR.
我们继续通过生命受体模型（MVR）对生存曲线进行分析。已考虑主要类型的生存函数（E分布、TW分布和GM分布）。发现最大寿命取决于生命受体的阈值浓度。得出了最大寿命与失活、破坏和失活反应动力学参数之间的依赖关系方程。考虑了最大生存时间与种群初始大小的关系。通过E分布分析温度对生存曲线的影响。建立了描述热存活和热失活曲线的方程。得出了密度函数及其特征（众数和反众数年龄、不对称系数）与MVR参数之间的依赖关系方程。结果表明，E分布、TW分布和GM分布具有不同类型的不对称性。GM分布的不对称系数与MVR参数相关。假定死亡率和出生率曲线的对称性由MVR机制协调。
