Schroeder A P, Houlind K, Pedersen E M, Thuesen L, Nielsen T T, Egeblad H
Department of Cardiology, Aarhus University Hospital, Skejby, Denmark.
J Cardiovasc Magn Reson. 2000;2(1):43-9. doi: 10.3109/10976640009148672.
We elucidated whether exposure to cardiac magnetic resonance imaging (MRI) of patients with implanted intracoronary stents is associated with increased risk of stent-thrombosis, stent-restenosis, or other cardiovascular complications. Forty-seven patients admitted with acute myocardial infarction (AMI) were studied. Twenty-three were included in a serial cardiac MRI study, using 1.5-T scanners with standard gradient systems. The remaining patients were control subjects who were matched for age and gender with the MRI group. All patient had intracoronary stents implanted in connection with primary angioplastic treatment (PTCA) of AMI (n = 21), secondary PTCA procedures due to recurrent angina (n = 22), or both (n = 4). In the MRI group (n = 23, aged 58 +/- 10 yr), MRI was carried out one to five times in each patient a median of 166 days (range, 1-501) after stent implantation. The control group comprised 24 patients, ages 59 +/- 11 yr. The incidences of stent-thrombosis, stent-restenosis, and other cardiovascular complications did not differ statistically significantly between the two groups. In the MRI group, stent-related thrombosis (n = 1) or restenosis (n = 7) was observed in eight cases a median of 102 days (range, 7-547) after MR examination and a median of 318 days (range, 138-713) after stent implantation, compared with nine cases in the control group (thrombosis, n = 1; restenosis, n = 8) observed a median of 147 days (range, 1-267) after stent implantation. No acute thromboembolic or other complication occurred in immediate connection with MRI. The follow-up time was 21.3 +/- 4.5 months. This small study shows no evidence of an MRI-related risk of stent-restenosis or other cardiovascular complications, not even if cardiac MRI is performed early after stent implantation.
我们阐明了植入冠状动脉支架的患者接受心脏磁共振成像（MRI）检查是否会增加支架血栓形成、支架再狭窄或其他心血管并发症的风险。对47例急性心肌梗死（AMI）患者进行了研究。23例患者纳入了系列心脏MRI研究，使用配备标准梯度系统的1.5-T扫描仪。其余患者为对照组，在年龄和性别上与MRI组匹配。所有患者均因AMI的初次血管成形术治疗（PTCA）（n = 21）、复发性心绞痛导致的二次PTCA手术（n = 22）或两者皆有（n = 4）而植入冠状动脉支架。在MRI组（n = 23，年龄58±10岁）中，每位患者在支架植入后中位166天（范围1 - 501天）进行了1至5次MRI检查。对照组包括24例患者，年龄59±11岁。两组之间支架血栓形成、支架再狭窄和其他心血管并发症的发生率在统计学上无显著差异。在MRI组中，8例患者在MR检查后中位102天（范围7 - 547天）、支架植入后中位318天（范围138 - 713天）观察到与支架相关的血栓形成（n = 1）或再狭窄（n = 7），而对照组有9例（血栓形成，n = 1；再狭窄，n = 8）在支架植入后中位147天（范围1 - 267天）观察到。在MRI检查后未立即发生急性血栓栓塞或其他并发症。随访时间为21.3±4.5个月。这项小型研究表明，没有证据显示MRI会增加支架再狭窄或其他心血管并发症的风险，即使在支架植入后早期进行心脏MRI检查也是如此。
