Jones A R, Connor D E
Department of Biochemistry, The University of Sydney, NSW, Australia.
Reprod Fertil Dev. 2000;12(7-8):355-9. doi: 10.1071/rd00116.
In 1945, Mann showed fructose to be the principal sugar in semen. For over half a century the means by which fructose is metabolized by sperm has been assumed to be by an initial phosphorylation catalysed by hexokinase, but this has never been substantiated. In the present study, by comparing the metabolism of glucose and fructose by both whole boar sperm and hypotonically treated cells, it is confirmed that fructose is phosphorylated by hexokinase to produce fructose 6-phosphate.
1945年，曼恩证明果糖是精液中的主要糖类。半个多世纪以来，一直认为精子代谢果糖的方式是首先由己糖激酶催化磷酸化，但这从未得到证实。在本研究中，通过比较公猪全精子和低渗处理细胞对葡萄糖和果糖的代谢，证实果糖被己糖激酶磷酸化生成6-磷酸果糖。
