García Aroca J, Alonso Calderón J L, García Redondo C, Rollán Villamarín V
Servicio de Cirugía Pediátrica, Hospital Niño Jesús, Avda. Menéndez Pelayo 65, 28009 Madrid.
Cir Pediatr. 2001 Jul;14(3):98-102.
We have studied 18 patients with anorexia nervosa with antroduodenal manometry for 24 hours and also 24 hours oesophageal pH studies. After the first 12 hours of measurements we started treatment with Cisapride (n = 8) or Erythromycin (n = 10) in a blind study. The results of measurements reveal a severe gastroesophageal reflux in 4 patients. Antroduodenal manometry showed dysfunctions in gastric motility, without relation with weight loss or duration of the disease. Cisapride and more so Erythromycin favor gastrointestinal motility.
我们对18例神经性厌食症患者进行了24小时的胃十二指肠测压以及24小时的食管pH值研究。在测量的前12小时后,我们在一项盲法研究中开始用西沙必利(n = 8)或红霉素(n = 10)进行治疗。测量结果显示4例患者存在严重的胃食管反流。胃十二指肠测压显示胃动力功能障碍,与体重减轻或疾病持续时间无关。西沙必利,尤其是红霉素,有利于胃肠动力。