Fanardzhian V V
L.A. Orbeli Institute of Physiology, National Academy of Sciences of Armenia, Yerevan.
Usp Fiziol Nauk. 2001 Apr-Jun;32(2):3-15.
Unilateral transection of the rubrospinal tract before lesion of the red nucleus or the ventrolateral thalamic nucleus has been shown to facilitate recovery of operantly conditioned reflexes and compensatory processes in rats. Such strengthening of the recovery plasticity and operantly conditioned was found when transection of the bulbar pyramide performed before ablation of the sensorimotor cortex. These influences are explained by activation of the rubroolivary projection, which is switching of descending cortico-rubrospinal system on the corticospinal system, and on the contrary. The general property of this phenomenon is that preliminary lesion of the peripheral part of the descending spinal projection to acquire a signal forestalling significance for mibilization of compensatory brain capacity in order to recovery the deficit of central link of the system.
在红核或腹外侧丘脑核损伤之前，对大鼠进行红核脊髓束的单侧横断已被证明可促进操作性条件反射和代偿过程的恢复。当在感觉运动皮层切除之前进行延髓锥体横断时，发现这种恢复可塑性和操作性条件反射得到了加强。这些影响可以通过红核橄榄体投射的激活来解释，即下行皮质-红核脊髓系统在皮质脊髓系统上的切换，反之亦然。这种现象的一般特性是，下行脊髓投射外周部分的初步损伤获得了一个信号，该信号对于动员代偿性脑容量以恢复系统中枢环节的缺陷具有预示意义。
