[身材矮小青春期前受试者垂体储备联合试验期间的血浆促黄体生成素、促卵泡生成素、促甲状腺激素、催乳素和皮质醇]

[Plasma LH, FSH, TSH, prolactin and cortisol during a combined test of pituitary reserve in prepubertal subjects with short stature].

作者信息

Esposito V, Bellastella A, D'Alessandro B, Santomassimo A M, Spagnoletti T, Cafaro M R

出版信息

Boll Soc Ital Biol Sper. 1978 Dec 30;54(24):2561-4.

Abstract

The effect of a combined test (insulin, TRH, LHRH) on plasma concentrations of LH, FSH, PRL, Cortisol was studied in 18 normal subjects in prepubescent state and in 65 patients in prepubescent state with short stature. In 6 subjects with short stature there was no change of LH, and in 7 subjects with short stature there was no change of FSH. In conclusion the combined test for pituitary stimulation provides an useful method for localizing the lesion in disorders of hypothalamo-pituitary axis.

摘要

在18名青春期前状态的正常受试者和65名青春期前身材矮小的患者中，研究了联合试验（胰岛素、促甲状腺激素释放激素、促黄体生成素释放激素）对促黄体生成素（LH）、促卵泡生成素（FSH）、催乳素（PRL）、皮质醇血浆浓度的影响。在6名身材矮小的受试者中，LH无变化，在7名身材矮小的受试者中，FSH无变化。总之，垂体刺激联合试验为下丘脑 - 垂体轴疾病的病变定位提供了一种有用的方法。