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Deep venous thrombosis prophylaxis is not indicated for laparoscopic cholecystectomy.腹腔镜胆囊切除术无需进行深静脉血栓形成预防。
JSLS. 2001 Jul-Sep;5(3):215-9.
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本文引用的文献

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Influence of pneumoperitoneum on the deep venous system during laparoscopy.腹腔镜检查期间气腹对深静脉系统的影响。
JSLS. 2000 Oct-Dec;4(4):291-5.
2
Preoperative use of enoxaparin and tirofiban: possible association with increased bleeding postbypass.术前使用依诺肝素和替罗非班:可能与体外循环后出血增加有关。
Anesthesiology. 1999 Sep;91(3):869-72. doi: 10.1097/00000542-199909000-00042.
3
Incidence of deep vein thrombosis after laparoscopic vs minilaparotomy cholecystectomy.腹腔镜胆囊切除术与小切口开腹胆囊切除术后深静脉血栓形成的发生率
Arch Surg. 1998 Sep;133(9):967-73. doi: 10.1001/archsurg.133.9.967.
4
Effect of low-molecular-weight heparin on serum concentrations of potassium.低分子量肝素对血清钾浓度的影响。
Lancet. 1997 Jul 26;350(9073):292-3. doi: 10.1016/s0140-6736(05)62260-x.
5
Enoxaparin-associated dermal necrosis: a consequence of cross-reactivity with heparin-mediated antibodies.
Ann Pharmacother. 1997 Mar;31(3):323-6. doi: 10.1177/106002809703100310.
6
Mortality and complications associated with laparoscopic cholecystectomy. A meta-analysis.腹腔镜胆囊切除术相关的死亡率和并发症。一项荟萃分析。
Ann Surg. 1996 Nov;224(5):609-20. doi: 10.1097/00000658-199611000-00005.
7
The incidence of deep venous thrombosis after laparoscopic cholecystectomy.腹腔镜胆囊切除术后深静脉血栓形成的发生率。
Med J Aust. 1996 Jun 3;164(11):652-4, 656.
8
Thromboembolic complications of laparoscopic cholecystectomy.
BMJ. 1993 Feb 20;306(6876):518-9. doi: 10.1136/bmj.306.6876.518-c.
9
Complications of laparoscopic cholecystectomy: a national survey of 4,292 hospitals and an analysis of 77,604 cases.腹腔镜胆囊切除术的并发症:对4292家医院的全国性调查及77604例病例分析
Am J Surg. 1993 Jan;165(1):9-14. doi: 10.1016/s0002-9610(05)80397-6.
10
Intermittent sequential pneumatic compression in prevention of venous stasis associated with pneumoperitoneum during laparoscopic cholecystectomy.间歇性序贯气压式压迫预防腹腔镜胆囊切除术期间与气腹相关的静脉淤滞
Arch Surg. 1993 Aug;128(8):914-8; discussion 918-9. doi: 10.1001/archsurg.1993.01420200088016.

腹腔镜胆囊切除术无需进行深静脉血栓形成预防。

Deep venous thrombosis prophylaxis is not indicated for laparoscopic cholecystectomy.

作者信息

Blake A M, Toker S I, Dunn E

机构信息

Methodist Medical Center of Dallas, Department of Surgery, Texas, USA.

出版信息

JSLS. 2001 Jul-Sep;5(3):215-9.

PMID:11548825
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3015441/
Abstract

OBJECTIVES

Recent publications have discussed the risk of deep venous thrombosis during laparoscopic cholecystectomy and the need for routine deep venous thrombosis (DVT) prophylaxis. The purpose of this study was to determine the incidence of clinically detectable DVT in patients undergoing laparoscopic cholecystectomy without a standard DVT prophylaxis regimen.

MATERIALS AND METHODS

We performed completed laparoscopic cholecystectomy in 587 patients over a 4-year period. Eighteen of these patients received some form of perioperative DVT prophylaxis, and 569 patients did not. Routine screening with a duplex Doppler was not used. Patients were followed postoperatively for 4 weeks after discharge from the hospital.

RESULTS

In an average of 4 weeks follow-up, 31 complications and 4 deaths were reported. These complications included wound infection (16), postoperative bleeding (3), persistent pain (3), pneumonia (3), retained CBD stones (2), asthma (1), papillary stenosis (1), ileus (1), and intraoperative bowel injury (1). None of the 587 patients in this study had symptoms of DVT or pulmonary embolism.

DISCUSSION

Despite the fact that DVT in this patient population is rare, many reports suggest the use of routine DVT prophylaxis with sequential compression devices (SCDs) or low-molecular-weight heparin (LMWH). Because no clinically detectable evidence was found of DVT in our study group despite the lack of any perioperative DVT prophylaxis, we question whether routine DVT prophylaxis is indicated or cost effective for routine laparoscopic cholecystectomy. A large prospective trial addressing this question is needed.

摘要

目的

近期的出版物讨论了腹腔镜胆囊切除术期间深静脉血栓形成的风险以及常规进行深静脉血栓形成(DVT)预防的必要性。本研究的目的是确定在未采用标准DVT预防方案的情况下接受腹腔镜胆囊切除术患者中临床可检测到的DVT的发生率。

材料与方法

我们在4年期间对587例患者进行了完整的腹腔镜胆囊切除术。其中18例患者接受了某种形式的围手术期DVT预防,569例患者未接受。未使用双功多普勒进行常规筛查。患者出院后接受了4周的术后随访。

结果

在平均4周的随访中,报告了31例并发症和4例死亡。这些并发症包括伤口感染(16例)、术后出血(3例)、持续性疼痛(3例)、肺炎(3例)、胆总管结石残留(2例)、哮喘(1例)、乳头狭窄(1例)、肠梗阻(1例)和术中肠损伤(1例)。本研究中的587例患者均无DVT或肺栓塞症状。

讨论

尽管该患者群体中DVT罕见,但许多报告建议使用序贯加压装置(SCD)或低分子肝素(LMWH)进行常规DVT预防。由于我们的研究组中尽管缺乏任何围手术期DVT预防,但未发现临床可检测到的DVT证据,我们质疑常规腹腔镜胆囊切除术常规进行DVT预防是否必要或具有成本效益。需要进行一项大型前瞻性试验来解决这个问题。