Lepistö P, Alho A
Acta Chir Scand. 1975;141(4):245-50.
A series of 444 patients with multiple blunt injuries were analysed with respect to the incidence of symptoms and signs generally described in connection with the fat embolism syndrome. During hospital treatment, a diagnosis of fat embolism was established for 47 patients and suspected in 23 patients. In retrospect, the latter patients had a morbid picture similar to that of the former. Hypoxia, anemia, disturbances of consciousness, and hyperpyrexia were constant signs. A high incidnece of petechiae and snowstorm infiltrations of the lung was also found. These six signs showed a marked tendency to combine; and placed the fat embolism patients in a distinctive group. The most susceptible patients were young adults with diaphyseal fractures of the lower extremities. Hypoxia was the most important early sign and the most important factor in terms of treatment. We conclude that the fact embolism syndrome is a clinical entity and that its diagnosis can be made on the basis of the symptom complex.
对444例多处钝器伤患者进行了分析，以了解与脂肪栓塞综合征相关的一般症状和体征的发生率。在住院治疗期间，47例患者被确诊为脂肪栓塞，23例患者被怀疑患有脂肪栓塞。回顾性分析发现，后一组患者的病情与前一组相似。缺氧、贫血、意识障碍和高热是常见症状。还发现瘀点和肺部暴风雪样浸润的发生率很高。这六种症状有明显的合并倾向；使脂肪栓塞患者形成一个独特的群体。最易患的患者是下肢骨干骨折的年轻人。缺氧是最重要的早期症状，也是治疗方面最重要的因素。我们得出结论，脂肪栓塞综合征是一种临床实体，其诊断可基于症状复合体做出。
