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选择性后根切断术及鞘内注射巴氯芬治疗痉挛

Selective posterior rhizotomy and intrathecal baclofen for the treatment of spasticity.

作者信息

von Koch C S, Park T S, Steinbok P, Smyth M, Peacock W J

机构信息

Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143-0112, USA.

出版信息

Pediatr Neurosurg. 2001 Aug;35(2):57-65. doi: 10.1159/000050392.

Abstract

Spasticity occurs in children and adults due to a wide range of conditions, including cerebral palsy, head and spinal cord trauma, cerebrovascular accidents and multiple sclerosis. Multiple treatment options have been described, including medical and surgical treatments. Medical treatments include intramuscular botulinum A toxin, oral baclofen and supportive bracing. Surgical approaches include selective posterior rhizotomy, intrathecal baclofen and orthopedic procedures to address deformities. Many reports have been published on these different treatment options, but rarely has a comparison been made between them. Therefore, this review is aimed at comparing selective posterior rhizotomy and intrathecal baclofen injection for spasticity due to cerebral palsy, especially in children.

摘要

痉挛在儿童和成人中因多种情况而发生,包括脑瘫、头部和脊髓创伤、脑血管意外以及多发性硬化症。已经描述了多种治疗选择,包括药物治疗和手术治疗。药物治疗包括肌肉注射A型肉毒杆菌毒素、口服巴氯芬和支撑性支具。手术方法包括选择性后根切断术、鞘内注射巴氯芬以及矫正畸形的骨科手术。关于这些不同治疗选择已经发表了许多报告,但很少对它们进行比较。因此,本综述旨在比较选择性后根切断术和鞘内注射巴氯芬治疗脑瘫所致痉挛的效果,尤其是在儿童中。

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