[The effects of methodical factors on the microphonic potential in the guinea pig cochlea with perfusion of perilymph].

The decreas in microphonic potentials detected from the round window (RMP) is negligible only if the bores are located very close to the round window, whereas it will increase with increasing distance from it. Only at pressures of more than +/- 30 cm water column, in rare cases even below that, will a sharp decrease in the RMP occur, possibly because of a lesion of either the oval or the round windown membrane. At a perfusion pressure above +5.6 cm water column, the perfusion liquid will enter the cerebrospinal fluid space. At a lower pressure the perfusion liquid is diluted by cerebrospinal fluid via the cochlear aqueduct. The perfusion speed of 1 to 50 mul/min has no effect on the function of the organ of Corti.