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继发进展型多发性硬化症患者总体生活质量的决定因素:一项纵向研究

Determinants of overall quality of life in secondary progressive MS: a longitudinal study.

作者信息

O'Connor P, Lee L, Ng P T, Narayana P, Wolinsky J S

机构信息

St. Michael's Hospital, Sunnybrook, Toronto, Ontario, Canada.

出版信息

Neurology. 2001 Sep 11;57(5):889-91. doi: 10.1212/wnl.57.5.889.

Abstract

Twenty-nine patients with secondary progressive MS underwent monthly assessment with Expanded Disability Status Scale (EDSS), MS Functional Composite (MSFC), MS Quality of Life-54, and cranial MRI over 6 months. Overall quality of life (OQOL) correlated highly with emotional well-being, the mental health composite, health distress, and the physical health composite. In contrast, there was no statistical evidence of consistent correlation between OQOL and EDSS, MSFC, or MR outcome measures.

摘要

29例继发进展型多发性硬化症患者在6个月内每月接受扩展残疾状态量表(EDSS)、多发性硬化症功能综合评分(MSFC)、多发性硬化症生活质量-54量表评估及头颅MRI检查。总体生活质量(OQOL)与情绪健康、心理健康综合评分、健康困扰及身体健康综合评分高度相关。相比之下,没有统计学证据表明OQOL与EDSS、MSFC或MRI结果测量之间存在一致的相关性。

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