Koga M, Matsuoka T, Katayama K, Takeda K, Nakata M, Sase M, Kato H, Furukawa S
Department of Pediatrics, Yamaguchi University School of Medicine, Yamaguchi, Japan.
Am J Perinatol. 2001 Aug;18(5):237-40. doi: 10.1055/s-2001-16988.
We investigated whether intrauterine parvovirus B19 infection is associated with premature birth by evaluating parvovirus B19 antibodies and DNA in umbilical cord blood from 76 premature infants. We performed enzyme-linked immunoadsorbent (ELISA) and polymerase chain reaction (PCR) assays to detect B19-specific IgM antibodies and parvovirus DNA. No parvovirus DNA was detected in cord blood sera, and no sample was positive for anti-parvovirus B19 IgM antibodies. Parvovirus appears unlikely to lead to premature birth.
我们通过评估76例早产婴儿脐带血中的细小病毒B19抗体和DNA，研究宫内细小病毒B19感染是否与早产有关。我们进行了酶联免疫吸附（ELISA）和聚合酶链反应（PCR）检测，以检测B19特异性IgM抗体和细小病毒DNA。在脐带血血清中未检测到细小病毒DNA，且没有样本抗细小病毒B19 IgM抗体呈阳性。细小病毒似乎不太可能导致早产。
