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嗅觉系统如何理解气味。

How the olfactory system makes sense of scents.

作者信息

Firestein S

机构信息

Department of Biological Sciences, Columbia University, New york, New York 10027, USA.

出版信息

Nature. 2001 Sep 13;413(6852):211-8. doi: 10.1038/35093026.

Abstract

The human nose is often considered something of a luxury, but in the rest of the animal world, from bacteria to mammals, detecting chemicals in the environment has been critical to the successful organism. An indication of the importance of olfactory systems is the significant proportion - as much as 4% - of the genomes of many higher eukaryotes that is devoted to encoding the proteins of smell. Growing interest in the detection of diverse compounds at single-molecule levels has made the olfactory system an important system for biological modelling.

摘要

人类的鼻子常常被视为一种奢侈品,但在动物界的其他生物中,从细菌到哺乳动物,检测环境中的化学物质对生物的生存繁衍至关重要。嗅觉系统重要性的一个体现是,许多高等真核生物基因组中有相当比例(高达4%)用于编码嗅觉蛋白。人们对单分子水平检测多种化合物的兴趣与日俱增,这使得嗅觉系统成为生物建模的重要系统。

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