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LRP: a multifunctional scavenger and signaling receptor.

作者信息

Herz J, Strickland D K

机构信息

Department of Molecular Genetics, Dallas, Texas, USA.

出版信息

J Clin Invest. 2001 Sep;108(6):779-84. doi: 10.1172/JCI13992.

DOI:10.1172/JCI13992
PMID:11560943
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC200939/
Abstract
摘要

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本文引用的文献

1
The low density lipoprotein receptor-related protein modulates levels of matrix metalloproteinase 9 (MMP-9) by mediating its cellular catabolism.低密度脂蛋白受体相关蛋白通过介导细胞分解代谢来调节基质金属蛋白酶9（MMP-9）的水平。
J Biol Chem. 2001 May 4;276(18):15498-503. doi: 10.1074/jbc.M100121200. Epub 2001 Feb 2.
2
Tyrosine-phosphorylated low density lipoprotein receptor-related protein 1 (Lrp1) associates with the adaptor protein SHC in SRC-transformed cells.酪氨酸磷酸化的低密度脂蛋白受体相关蛋白1（Lrp1）在SRC转化细胞中与衔接蛋白SHC结合。
J Biol Chem. 2001 Jun 1;276(22):19119-25. doi: 10.1074/jbc.M011437200. Epub 2001 Mar 20.
3
Apolipoprotein E receptors: linking brain development and Alzheimer's disease.载脂蛋白E受体：连接大脑发育与阿尔茨海默病
Nat Rev Neurosci. 2000 Oct;1(1):51-8. doi: 10.1038/35036221.
4
The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling.组织型纤溶酶原激活剂的蛋白水解活性增强了NMDA受体介导的信号传导。
Nat Med. 2001 Jan;7(1):59-64. doi: 10.1038/83358.
5
Clearance of Alzheimer's amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier.低密度脂蛋白受体相关蛋白-1在血脑屏障处清除大脑中的阿尔茨海默病淀粉样β（1-40）肽。
J Clin Invest. 2000 Dec;106(12):1489-99. doi: 10.1172/JCI10498.
6
Extracellular matrix metalloproteinase 2 levels are regulated by the low density lipoprotein-related scavenger receptor and thrombospondin 2.细胞外基质金属蛋白酶2的水平受低密度脂蛋白相关清道夫受体和血小板反应蛋白2的调节。
J Biol Chem. 2001 Mar 16;276(11):8403-8. doi: 10.1074/jbc.M008925200. Epub 2000 Dec 11.
7
Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands.由低密度脂蛋白受体相关蛋白介导的HIV-1反式激活蛋白摄取破坏了受体配体的神经元代谢平衡。
Nat Med. 2000 Dec;6(12):1380-7. doi: 10.1038/82199.
8
Modulation of amyloid beta-protein clearance and Alzheimer's disease susceptibility by the LDL receptor-related protein pathway.低密度脂蛋白受体相关蛋白途径对β-淀粉样蛋白清除及阿尔茨海默病易感性的调节作用
J Clin Invest. 2000 Nov;106(9):1159-66. doi: 10.1172/JCI11013.
9
The endocytic receptor protein LRP also mediates neuronal calcium signaling via N-methyl-D-aspartate receptors.内吞受体蛋白LRP还通过N-甲基-D-天冬氨酸受体介导神经元钙信号传导。
Proc Natl Acad Sci U S A. 2000 Oct 10;97(21):11551-6. doi: 10.1073/pnas.200238297.
10
The reelin receptor ApoER2 recruits JNK-interacting proteins-1 and -2.reelin受体ApoER2招募与JNK相互作用的蛋白1和蛋白2。
J Biol Chem. 2000 Aug 18;275(33):25625-32. doi: 10.1074/jbc.M004119200.