Popova E N, Vavilov A M
Arkh Anat Gistol Embriol. 1975 Mar;68(3):65-71.
Morphological maturation of the rat's caudate nucleus and formation of cholinergic system in it were studied in postnatal ontogenesis. Under investigation were newborn rats, 7, 14, 21 day old rats and adult animals. The growth and maturation of the caudate nucleys were most intesne during the first two postnatal weeks, it was somewhat descreased by the beginning of the third week and continued in later terms as well. The structure of dendrites and axons became complicated during the first two weeks, the axo-dendritic contacts being also formed. The neuron structure in 14 days old rats was similar to that of adult animals. The activity of acetylcholinesterase in the caudate nucleus of 7 and 14 days rats was not great. It sharply increased by the 17th day and reached the level of adults with 3 weeks after birth. Possible correlations of the morpho-chemical maturation of the caudate nucleus and formation of motor activity in rats is discussed.
研究了大鼠尾状核在生后个体发育过程中的形态成熟及其胆碱能系统的形成。研究对象为新生大鼠、7日龄、14日龄、21日龄大鼠及成年动物。尾状核的生长和成熟在生后前两周最为强烈，到第三周开始时有所减缓，并在之后的时期继续进行。树突和轴突的结构在头两周变得复杂，同时也形成了轴突 - 树突连接。14日龄大鼠的神经元结构与成年动物相似。7日龄和14日龄大鼠尾状核中的乙酰胆碱酯酶活性不高。在第17天时急剧增加，并在出生后3周达到成年水平。文中讨论了大鼠尾状核形态化学成熟与运动活动形成之间可能的相关性。
