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急性等容性血液稀释对腹主动脉瘤修复术中输血需求的影响。

The effect of acute normovolaemic haemodilution on blood transfusion requirements in abdominal aortic aneurysm repair.

作者信息

Wolowczyk L, Lewis D R, Nevin M, Smith F C, Baird R N, Lamont P M

机构信息

Department of Vascular Surgery, Bristol Royal Infirmary, Bristol, UK.

出版信息

Eur J Vasc Endovasc Surg. 2001 Oct;22(4):361-4. doi: 10.1053/ejvs.2001.1457.

Abstract

OBJECTIVE

to evaluate the impact of acute normovolaemic haemodilution (ANH) on the blood transfusion requirements in elective abdominal aortic aneurysm (AAA) repair in a single vascular unit.

METHODS

thirty-two patients underwent ANH during elective AAA repair between 1992 and 1997. The operation was performed by the same surgeon/anaesthetist team in 75% of cases. Their demographic details, type of aneurysm (infra-renal or supra-renal), preoperative blood cross match, use of intra-operative red cell salvage, blood loss, peri-operative bank blood requirements, pre-op and on-discharge haemoglobin levels and post-operative outcome were recorded. The results were compared to a group of 40 randomly selected patients (to represent the unit average) who underwent elective AAA repair by variable surgeon/anaesthetist teams without ANH in the same time period.

RESULTS

there were more supra-renal AAA repairs in the ANH group (8/32) than in the non-ANH group (0/40, p<0.01). ANH patients required significantly less blood transfusion peri-operatively (median 2 units) than the non-ANH patients (median 3 units, p=0.02). There were no other significant differences between the variables measured.

CONCLUSION

these results suggest that a dedicated team can achieve significant reductions in the use of heterologous blood transfusion compared to the vascular unit average experience by the effective use of ANH.

摘要

目的

评估急性等容性血液稀释(ANH)对单个血管单元择期腹主动脉瘤(AAA)修复术中输血需求的影响。

方法

1992年至1997年期间,32例患者在择期AAA修复术中接受了ANH。75%的病例由同一外科医生/麻醉医生团队进行手术。记录了他们的人口统计学细节、动脉瘤类型(肾下或肾上)、术前血型交叉配血、术中红细胞回收利用情况、失血量、围手术期库血需求量、术前和出院时血红蛋白水平以及术后结果。将结果与同期40例随机选择的患者(代表该单元平均水平)进行比较,这些患者由不同的外科医生/麻醉医生团队进行择期AAA修复术,未接受ANH。

结果

ANH组中肾上AAA修复术的例数(8/32)多于非ANH组(0/40,p<0.01)。ANH患者围手术期所需输血量(中位数为2单位)明显少于非ANH患者(中位数为3单位,p=0.02)。所测量的变量之间没有其他显著差异。

结论

这些结果表明,与血管单元的平均经验相比,一个专业团队通过有效使用ANH可显著减少异体输血的使用。

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