Wolowczyk L, Lewis D R, Nevin M, Smith F C, Baird R N, Lamont P M
Department of Vascular Surgery, Bristol Royal Infirmary, Bristol, UK.
Eur J Vasc Endovasc Surg. 2001 Oct;22(4):361-4. doi: 10.1053/ejvs.2001.1457.
to evaluate the impact of acute normovolaemic haemodilution (ANH) on the blood transfusion requirements in elective abdominal aortic aneurysm (AAA) repair in a single vascular unit.
thirty-two patients underwent ANH during elective AAA repair between 1992 and 1997. The operation was performed by the same surgeon/anaesthetist team in 75% of cases. Their demographic details, type of aneurysm (infra-renal or supra-renal), preoperative blood cross match, use of intra-operative red cell salvage, blood loss, peri-operative bank blood requirements, pre-op and on-discharge haemoglobin levels and post-operative outcome were recorded. The results were compared to a group of 40 randomly selected patients (to represent the unit average) who underwent elective AAA repair by variable surgeon/anaesthetist teams without ANH in the same time period.
there were more supra-renal AAA repairs in the ANH group (8/32) than in the non-ANH group (0/40, p<0.01). ANH patients required significantly less blood transfusion peri-operatively (median 2 units) than the non-ANH patients (median 3 units, p=0.02). There were no other significant differences between the variables measured.
these results suggest that a dedicated team can achieve significant reductions in the use of heterologous blood transfusion compared to the vascular unit average experience by the effective use of ANH.
评估急性等容性血液稀释(ANH)对单个血管单元择期腹主动脉瘤(AAA)修复术中输血需求的影响。
1992年至1997年期间,32例患者在择期AAA修复术中接受了ANH。75%的病例由同一外科医生/麻醉医生团队进行手术。记录了他们的人口统计学细节、动脉瘤类型(肾下或肾上)、术前血型交叉配血、术中红细胞回收利用情况、失血量、围手术期库血需求量、术前和出院时血红蛋白水平以及术后结果。将结果与同期40例随机选择的患者(代表该单元平均水平)进行比较,这些患者由不同的外科医生/麻醉医生团队进行择期AAA修复术,未接受ANH。
ANH组中肾上AAA修复术的例数(8/32)多于非ANH组(0/40,p<0.01)。ANH患者围手术期所需输血量(中位数为2单位)明显少于非ANH患者(中位数为3单位,p=0.02)。所测量的变量之间没有其他显著差异。
这些结果表明,与血管单元的平均经验相比,一个专业团队通过有效使用ANH可显著减少异体输血的使用。