Ho Pei, Ting Albert C W, Cheng Stephen W K
Division of Vascular Surgery, Department of Surgery, Queen Mary Hospital, University of Hong Kong Medical Centre, Hong Kong.
ANZ J Surg. 2004 Aug;74(8):631-4. doi: 10.1111/j.1445-1433.2004.03117.x.
Intraoperative blood loss and transfusion are known determinants of mortality and morbidity of elective abdominal aortic aneurysm (AAA) repair. The present study analysed the pattern of blood loss and transfusion and evaluated the risk factors of blood loss during open repair of infrarenal AAA.
Blood loss, transfusion and fluid replacement during elective open repair operation for patients with infrarenal AAA were correlated to demographic data, operative findings and procedural information.
A total of 129 patients with a mean age of 71 years was analysed. The mean blood loss was 1000 +/- 887 mL (200-6000 mL). Blood transfusion, with a mean transfusion volume of 400 +/- 591 mL (0-3000 mL), was required in 46% of patients. Univariate analysis showed that bodyweight, renal impairment, low haemoglobin and platelet counts, iliac artery involvement, large aneurysm, bifurcated graft, large graft diameter, prolonged aortic clamp time and long operation time were associated with a higher blood loss. A haemoglobin level of <10.5 g/dL (relative risk (RR): 4.6), platelet count <130 x 10(9)/L (RR: 3.9), aortic clamp time >50 min (RR: 15), total operation time >200 min (RR: 11) and type of graft (RR: 3.5) were identified as independent determinants of blood loss on multivariate analysis.
Intraoperative blood loss in elective infrarenal aneurysm surgery is influenced by patients' haematological parameters, distal involvement of aneurysm and degree of difficulty of operation.
术中失血和输血是择期腹主动脉瘤(AAA)修复术死亡率和发病率的已知决定因素。本研究分析了失血和输血模式,并评估了肾下腹主动脉瘤开放修复术中失血的危险因素。
将肾下腹主动脉瘤患者择期开放修复手术期间的失血、输血和液体补充情况与人口统计学数据、手术发现和手术信息相关联。
共分析了129例平均年龄为71岁的患者。平均失血量为1000±887毫升(200 - 6000毫升)。46%的患者需要输血,平均输血量为400±591毫升(0 - 3000毫升)。单因素分析显示,体重、肾功能损害、血红蛋白和血小板计数低、髂动脉受累、大动脉瘤、分叉移植物、大移植物直径、主动脉夹闭时间延长和手术时间长与失血较多有关。多因素分析确定血红蛋白水平<10.5克/分升(相对危险度(RR):4.6)、血小板计数<130×10⁹/L(RR:3.9)、主动脉夹闭时间>50分钟(RR:15)、总手术时间>200分钟(RR:11)和移植物类型(RR:3.5)是失血的独立决定因素。
择期肾下腹主动脉瘤手术中的术中失血受患者血液学参数、动脉瘤远端受累情况和手术难度的影响。