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急性冠状动脉综合征中普通肝素与低分子量肝素的比较

[Non-fractionated heparin versus low molecular weight heparin in acute coronary syndromes].

作者信息

González Pacheco H

机构信息

Servicio de Urgencias y Unidad Coronaria, Instituto Nacional de Cardiología Ignacio Chávez, INCICH, Juan Badiano No. 1, 14080 México, D.F.

出版信息

Arch Cardiol Mex. 2001 Jan-Mar;71 Suppl 1:S63-8.

PMID:11565348
Abstract

This article reviews the usefulness of heparins in the management of patients with acute coronary syndromes. Low molecular weight heparins have a series of advantages over unfractionated heparins, and evidences show that they are more effective than placebo and equal to unfractionated heparin in diminishing the incidence of acute myocardial infarction or death. Evidences that the effectiveness of the low molecular weight heparins are superior is limited to enoxaparin and the most benefited group is the stratified one as high risk.

摘要

本文综述了肝素在急性冠脉综合征患者治疗中的应用价值。低分子量肝素相对于普通肝素具有一系列优势,且有证据表明,在降低急性心肌梗死或死亡发生率方面,低分子量肝素比安慰剂更有效,与普通肝素相当。低分子量肝素疗效更优的证据仅限于依诺肝素,且受益最大的群体是高危分层患者。

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