[切-东-施综合征一例中的粒细胞干细胞]
[Granulocyte stem cells in a case of Chediak-Higashi-Steinbrinck syndrome].
作者信息
Parmentier C, Micheau C, Morardet N, Brossel-Morel S
出版信息
Biomedicine. 1975 Feb 28;23(2):59-63.
PMID:1156630
Abstract
Bone marrow from a child with Chediak-Higashi-Steinbrinck disease was cultured. It was found that all cells with granulocytic colony forming ability were affected by the disease. Cytoplasmic vacuoles were identified as lysosomes by their cytochemical staining. The cloning rates suggest that granulopoiesis is largely ineffective.
摘要
对一名患有切-东-施病的儿童的骨髓进行了培养。发现所有具有粒细胞集落形成能力的细胞都受到了该疾病的影响。通过细胞化学染色将细胞质空泡鉴定为溶酶体。克隆率表明粒细胞生成在很大程度上是无效的。
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