修饰的二核苷四膦酸酯，新型潜在的HIV逆转录酶抑制剂。
Modified dinucleoside tetraphosphonates, new potential inhibitors of HIV reverse transcriptase.
作者信息
Shirokova E A, Khandazhinskaya A L, Skoblov Y S, Goryunova L Y, Beabealashvilli R S, Krayevsky A A
机构信息
Engelhardt Instiute of Molecular Biology, Russian Academy of Sciences, 32 Vavilov St., Moscow 117984, Russia.
出版信息
Nucleosides Nucleotides Nucleic Acids. 2001 Apr-Jul;20(4-7):1033-6. doi: 10.1081/NCN-100002485.
PMID:11569477
Abstract
New gamma-substituted analogues of dNTP were synthesized and their enzymatic stability and antiviral properties were evaluated.
摘要
合成了新型γ-取代的脱氧核苷三磷酸类似物，并对其酶稳定性和抗病毒特性进行了评估。
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