焦磷酸盐和双膦酸盐的 P1，P2-二咪唑基衍生物——合成、性质及其在二核苷四磷酸和类似物制备中的应用。
P1,P2-diimidazolyl derivatives of pyrophosphate and bis-phosphonates--synthesis, properties, and use in preparation of dinucleoside tetraphosphates and analogs.
机构信息
GLSynthesis Inc., One Innovation Dr, Worcester, MA 01605, USA.
出版信息
Org Biomol Chem. 2011 Feb 7;9(3):730-8. doi: 10.1039/c0ob00542h. Epub 2010 Nov 17.
Abstract
P(1),P(2)-Diimidazolyl derivatives of pyrophosphate and halomethylene-bis-phosphonates have been synthesized and characterized, and the mechanism of their formation was studied. These reagents enable synthesis of dinucleoside tetraphosphates and tetraphosphonates conveniently and in high yields.
摘要
已经合成并表征了焦磷酸盐和卤亚甲基双膦酸的 P(1),P(2)-二咪唑基衍生物，并研究了它们的形成机制。这些试剂可方便地以高产率合成二核苷四磷酸酯和四膦酸酯。
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