Belliveau R E, Spencer R P
Cancer. 1975 Aug;36(2):359-63. doi: 10.1002/1097-0142(197508)36:2<359::aid-cncr2820360210>3.0.co;2-1.
The value of bone scanning with 99mTc-polyphosphate was assessed in 186 patients with various types of tumors. The sensitivity of this technique was greater than that of metastatic roentgenographic series and the reported results of 85-Sr-bone scans, in the detection of osseous involvement by tumors. Three cases with normal bone scans and abnormal roentgenographic studies illustrated the necessity and complementary value of comparing bone scan findings with radiographic studies. Patients with carcinoma of the breast, lung, or prostate displayed characteristic patterns of bone involvement by their tumors. The importance of clinical information, including bone symptoms, antecedent bone disease, and serum calcium and alkaline phosphatase, was stressed in the detection and interpretation of bone scan abnormalities.
对186例患有各种类型肿瘤的患者进行了99mTc-多聚磷酸盐骨扫描价值的评估。在检测肿瘤的骨受累情况方面，该技术的敏感性高于转移性X线检查系列以及报道的85-Sr骨扫描结果。3例骨扫描正常但X线检查异常的病例说明了将骨扫描结果与X线检查结果进行比较的必要性和互补价值。乳腺癌、肺癌或前列腺癌患者表现出其肿瘤累及骨骼的特征性模式。强调了临床信息（包括骨症状、既往骨疾病以及血清钙和碱性磷酸酶）在骨扫描异常检测和解读中的重要性。
