Odeh M, Misselevich I, Oliven A
Department of Internal Medicine B, Bnai Zion Medical Center, and Technion Faculty of Medicine, Israel Institute of Technology, Haifa.
Angiology. 2001 Sep;52(9):641-4. doi: 10.1177/000331970105200909.
An elderly patient with paraneoplastic cutaneous leukocytoclastic vasculitis (CLV) leading to the discovery of an as-yet asymptomatic, potentially surgically curable squamous cell carcinoma of the lung is presented. This type of vasculitis has not been previously described in association with this type of lung cancer. Since vasculitic paraneoplastic syndromes, including CLV, may develop before the clinical presentation of malignant tumors, the present case and others previously reported strongly suggest that in apparently idiopathic CLV, patients should be evaluated for the presence of occult malignancy that could be curable by early detection.
本文介绍了一位老年患者,其患有副肿瘤性皮肤白细胞破碎性血管炎(CLV),最终发现了一例尚未出现症状、可能通过手术治愈的肺鳞状细胞癌。此前尚未有这种类型的血管炎与这种类型肺癌相关的报道。由于包括CLV在内的血管炎性副肿瘤综合征可能在恶性肿瘤临床表现之前出现,本病例及其他先前报道的病例强烈提示,对于明显特发性CLV患者,应评估是否存在可通过早期检测治愈的隐匿性恶性肿瘤。