Shin S J, Sheikh F S, Allenby P A, Rosen P P
Department of Pathology, New York Presbyterian Hospital-Weill Medical College of Cornell University, New York, NY 10021, USA.
Arch Pathol Lab Med. 2001 Oct;125(10):1372-4. doi: 10.5858/2001-125-1372-ISJCAI.
Mammary carcinoma arising in ectopic breast tissue is an uncommon occurrence. Most reported cases have involved ductal carcinoma, but other types, such as medullary, papillary, and lobular carcinomas, have been described. For pathologists, the diagnosis of mammary carcinoma arising in ectopic breast tissue can be difficult, especially in the axilla, where carcinoma of adnexal origin must be excluded. We describe a 46-year-old woman who developed invasive (juvenile) secretory carcinoma in ectopic right axillary breast tissue and micrometastatic carcinoma in an ipsilateral axillary lymph node. The carcinoma arose in a right axillary mass that had been present for 8 years, from which she had secreted fluid during prior breast-feeding. To our knowledge, this is the first report of secretory carcinoma arising in axillary breast tissue to be documented in the current literature.
异位乳腺组织发生的乳腺癌是一种罕见情况。大多数报道的病例为导管癌，但也描述了其他类型，如髓样癌、乳头状癌和小叶癌。对于病理学家来说，诊断异位乳腺组织发生的乳腺癌可能很困难，尤其是在腋窝，必须排除附属器来源的癌。我们描述了一名46岁女性，她在异位的右侧腋窝乳腺组织中发生了浸润性（幼年型）分泌性癌，并在同侧腋窝淋巴结中发生了微转移癌。该癌起源于一个已存在8年的右侧腋窝肿块，她曾在先前哺乳期间从该肿块中分泌液体。据我们所知，这是当前文献中首次记录的腋窝乳腺组织发生分泌性癌的报告。
