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脊髓损伤男性的性功能

Sexual function in spinal cord lesioned men.

作者信息

Biering-Sørensen F, Sønksen J

机构信息

Clinic for Para- and Tetraplegia, Department TH, The Neuroscience Centre, Rigshospitalet, Copenhagen University Hospital, Havnevej 25, DK-3100 Hornbaek, Copenhagen, Denmark.

出版信息

Spinal Cord. 2001 Sep;39(9):455-70. doi: 10.1038/sj.sc.3101198.

Abstract

STUDY DESIGN

Review of literature.

OBJECTIVE

To review the physical aspects related to penile erection, ejaculatory dysfunction, semen characteristics, and techniques for enhancement of fertility in spinal cord lesioned (SCL) men.

SETTING

Worldwide: individuals with traumatic as well as non-traumatic SCL.

RESULTS

Recommendations for management of erectile dysfunction in SCL men: If it is possible to obtain a satisfactory erection but of insufficient duration, then try to use a venous constrictor band to find out if this is sufficient to maintain the erection. Otherwise we recommend Sildenafil. If Sildenafil is not satisfactory then use intracavernous injection with prostaglandin E(1) (some SCL men may prefer cutaneous or intraurethral application). We discourage the implantation of penile prosthesis for the sole purpose of erection. Recommendations for management of ejaculatory dysfunction in SCL men: Penile vibratory stimulation (PVS) to induce ejaculation is recommended as first treatment choice. If PVS fails, SCL men should be referred for electroejaculation (EEJ). Semen characteristics: Impaired semen profiles with low motility rates are seen in the majority of SCL men. Recently reported data gives evidence of a decline in spermatogenesis and motility of ejaculated spermatozoa shortly after (few weeks) an acute SCL. It is suggested that some factors in the seminal plasma and/or disordered storage of spermatozoa in the seminal vesicles are mainly responsible for the impaired semen profiles in men with chronic SCL. Fertility: Home insemination with semen obtained by PVS and introduced intravaginally in order to achieve successful pregnancies may be an option for some SCL men and their partners. The majority of SCL men will further enhance their fertility potential when using either PVS or EEJ combined with assisted reproduction techniques such as intrauterine insemination or in vitro fertilization with or without intracytoplasmic sperm injection.

摘要

研究设计

文献综述。

目的

回顾与脊髓损伤(SCL)男性阴茎勃起、射精功能障碍、精液特征及提高生育能力技术相关的生理方面。

研究地点

全球范围:创伤性和非创伤性SCL患者。

结果

SCL男性勃起功能障碍的治疗建议:如果能够获得满意的勃起但持续时间不足,可尝试使用静脉收缩带,看是否足以维持勃起。否则,我们推荐使用西地那非。如果西地那非效果不佳,则采用前列腺素E(1)海绵体内注射(一些SCL男性可能更喜欢经皮或尿道内给药)。我们不主张仅为勃起而植入阴茎假体。SCL男性射精功能障碍的治疗建议:推荐阴茎振动刺激(PVS)诱导射精作为首选治疗方法。如果PVS失败,SCL男性应转诊接受电射精(EEJ)。精液特征:大多数SCL男性精液参数受损,活力率低。最近报道的数据表明,急性SCL后不久(几周内),射精精子的精子发生和活力下降。提示精浆中的某些因素和/或精囊内精子储存紊乱是慢性SCL男性精液参数受损的主要原因。生育能力:对于一些SCL男性及其伴侣来说,使用通过PVS获得并经阴道内注入的精液进行家庭授精以实现成功妊娠可能是一种选择。大多数SCL男性在使用PVS或EEJ结合辅助生殖技术(如宫内授精或体外受精,有无卵胞浆内单精子注射)时,其生育潜力将进一步提高。

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