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[90例脊髓损伤患者勃起功能障碍和射精功能障碍的管理评估]

[Evaluation of the management of erectile and ejaculatory dysfunction in a series of 90 patients with spinal cord injuries].

作者信息

Hadiji N, Benbouzid R, Previnaire J G, Leblond C, Mieusset R, Enjalbert M, Soler J M

机构信息

Centre Bouffard-vercelli-Cap Peyrefite, 66290 Cerbère, France.

出版信息

Prog Urol. 2013 Dec;23(17):1489-93. doi: 10.1016/j.purol.2013.08.316. Epub 2013 Sep 20.

Abstract

OBJECTIVE

To evaluate the erectile dysfunction and ejaculatory on patients injured in conus medullaris (CMI) and the efficacy of treatment.

METHODS

Ninety patients with injured conus medullaris underwent a retrospective and monocentric study. They have all an assessment of erectile dysfunction and ejaculatory by the International Index of Erectile Function (IIEF-15) and a clinic scenario. We evaluated the erection by a clinical scoring scale (Shrameck). Seventy-seven out of 90 (85.55%) had therapeutic tests to restore erection: prostaglandin (PGE1), phosphodiesterase type 5 inhibitors (PDE5) and Papaverine. Seventy-four out of 90 (82.22%) underwent a penile stimulation tests (VM) more or less associated with Midodrine(®) (alpha mimetic) to cause ejaculation with a systematic search of spermatozoa in urine. Data were entered and analyzed using Microsoft Office Excel.

RESULTS

Ninety patients with a complete lesion of the sacral metameres (S2S3S4) were included. They were responding to PGE1, PDE5, respectively 81.63% and 30.76%. The association VM/Midodrine(®) improves ejaculation in 52.63% of cases. Orgasm is absent in all our CMI.

CONCLUSION

In this series of BCM patients, we observed a good efficacy of PGE1 and PDE 5 on erection. We also observed positive results of vibromassage and alpha-agonists on ejaculation.

摘要

目的

评估圆锥马尾损伤(CMI)患者的勃起功能障碍和射精功能以及治疗效果。

方法

对90例圆锥马尾损伤患者进行回顾性单中心研究。通过国际勃起功能指数(IIEF - 15)和临床情况对他们的勃起功能障碍和射精功能进行评估。我们采用临床评分量表(Shrameck)评估勃起情况。90例患者中有77例(85.55%)进行了恢复勃起的治疗试验:前列腺素(PGE1)、5型磷酸二酯酶抑制剂(PDE5)和罂粟碱。90例患者中有74例(82.22%)进行了阴茎刺激试验(VM),或多或少联合使用了米多君(α - 激动剂)以诱导射精,并对尿液进行系统的精子检测。数据使用Microsoft Office Excel录入和分析。

结果

纳入90例骶节段(S2S3S4)完全损伤的患者。他们对PGE1、PDE5的有效率分别为81.63%和30.76%。VM/米多君联合使用使52.63%的患者射精功能改善。所有CMI患者均无性高潮。

结论

在这组CMI患者中,我们观察到PGE1和PDE5对勃起有良好疗效。我们还观察到振动按摩和α - 激动剂对射精有积极效果。

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