Hadiji N, Benbouzid R, Previnaire J G, Leblond C, Mieusset R, Enjalbert M, Soler J M
Centre Bouffard-vercelli-Cap Peyrefite, 66290 Cerbère, France.
Prog Urol. 2013 Dec;23(17):1489-93. doi: 10.1016/j.purol.2013.08.316. Epub 2013 Sep 20.
To evaluate the erectile dysfunction and ejaculatory on patients injured in conus medullaris (CMI) and the efficacy of treatment.
Ninety patients with injured conus medullaris underwent a retrospective and monocentric study. They have all an assessment of erectile dysfunction and ejaculatory by the International Index of Erectile Function (IIEF-15) and a clinic scenario. We evaluated the erection by a clinical scoring scale (Shrameck). Seventy-seven out of 90 (85.55%) had therapeutic tests to restore erection: prostaglandin (PGE1), phosphodiesterase type 5 inhibitors (PDE5) and Papaverine. Seventy-four out of 90 (82.22%) underwent a penile stimulation tests (VM) more or less associated with Midodrine(®) (alpha mimetic) to cause ejaculation with a systematic search of spermatozoa in urine. Data were entered and analyzed using Microsoft Office Excel.
Ninety patients with a complete lesion of the sacral metameres (S2S3S4) were included. They were responding to PGE1, PDE5, respectively 81.63% and 30.76%. The association VM/Midodrine(®) improves ejaculation in 52.63% of cases. Orgasm is absent in all our CMI.
In this series of BCM patients, we observed a good efficacy of PGE1 and PDE 5 on erection. We also observed positive results of vibromassage and alpha-agonists on ejaculation.
评估圆锥马尾损伤(CMI)患者的勃起功能障碍和射精功能以及治疗效果。
对90例圆锥马尾损伤患者进行回顾性单中心研究。通过国际勃起功能指数(IIEF - 15)和临床情况对他们的勃起功能障碍和射精功能进行评估。我们采用临床评分量表(Shrameck)评估勃起情况。90例患者中有77例(85.55%)进行了恢复勃起的治疗试验:前列腺素(PGE1)、5型磷酸二酯酶抑制剂(PDE5)和罂粟碱。90例患者中有74例(82.22%)进行了阴茎刺激试验(VM),或多或少联合使用了米多君(α - 激动剂)以诱导射精,并对尿液进行系统的精子检测。数据使用Microsoft Office Excel录入和分析。
纳入90例骶节段(S2S3S4)完全损伤的患者。他们对PGE1、PDE5的有效率分别为81.63%和30.76%。VM/米多君联合使用使52.63%的患者射精功能改善。所有CMI患者均无性高潮。
在这组CMI患者中,我们观察到PGE1和PDE5对勃起有良好疗效。我们还观察到振动按摩和α - 激动剂对射精有积极效果。