对氯苯氧异丁酸的气相色谱测定及其与紫外法的比较。
A gas-liquid chromatographic determination of p-chlorophenoxyisobutyric acid and its comparison to an ultra violet method.
作者信息
Bruderlein H, Robinson W T, Kraml M, Dvornik D
出版信息
Clin Biochem. 1975 Aug;8(4):261-72. doi: 10.1016/s0009-9120(75)92747-2.
PMID:1157294
Abstract
- A gas-liquid chromatographic procedure for the determination of p-chlorophenoxyisobutyric acid (CPIB) has been elaborated and compared to the UV spectrophotometric procedure of Barrett and Thorp. 2. Both methods are specific when used to determine CPIB levels in normal sera from laboratory animals or humans treated with clofibrate (Atromid-S). Serum from patients treated with other drugs or abnormal sera from patients affected with a variety of diseases will often contain high and fluctuating levels of non-specific UV absorbing substances and this usually precludes the use of the UV procedure. 3. The GLC method is also applicable to the analysis of CPIB in urine samples.
摘要
- 已精心制定了一种用于测定对氯苯氧异丁酸（CPIB）的气液色谱法，并与巴雷特和索普的紫外分光光度法进行了比较。2. 当用于测定用氯贝丁酯（安妥明）治疗的实验动物或人类的正常血清中的CPIB水平时，这两种方法都是特异的。用其他药物治疗的患者的血清或患有各种疾病的患者的异常血清通常会含有高且波动的非特异性紫外线吸收物质，这通常排除了使用紫外法的可能性。3. 气相色谱法也适用于尿样中CPIB的分析。
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