Fliss D M, Zucker G, Cohen J T, Gatot A
Skull Base Surgery Unit, Department of Otolaryngology-Head and Neck Surgery, Tel-Aviv Sourasky Medical Center, Sackler Faculty of Medicine Tel-Aviv University, Tel Aviv, Israel.
J Oral Maxillofac Surg. 2001 Oct;59(10):1171-5. doi: 10.1053/joms.2001.26720.
Because of the likelihood of meningitis and other intracranial complications, optimal treatment for a cerebrospinal fluid (CSF) fistula is to close the leak. The neurosurgical approach to the management of CSF rhinorrhea has been by intracranial access. Extracranial approaches are now gaining acceptance as the preferred method for initial treatment of CSF leakage, because the success rates are reasonable, and the morbidity is lower. This report describes the results of using such an approach.
The extended subcranial approach was used in 10 patients with CSF rhinorrhea. Selection criteria included defects of the anterior skull base greater than 15 mm in diameter, defects not accessible by endoscopes, fistula sites that could not be localized preoperatively, and multiple and transverse fractures of the cribriform region. Follow-up ranged from 8 to 23 months, with a mean of 17 months.
Resolution of rhinorrhea was achieved in 9 (90%) of the patients. Anosmia was the only postoperative complication, occurring in 8 patients.
The authors conclude that the extended subcranial approach to the anterior skull base is a safe, versatile, and effective procedure for the surgical treatment of CSF rhinorrhea involving the anterior skull base.
由于存在脑膜炎及其他颅内并发症的可能性,脑脊液(CSF)瘘的最佳治疗方法是封闭漏口。神经外科处理脑脊液鼻漏的方法一直是采用颅内入路。颅外入路目前正逐渐被接受为脑脊液漏初始治疗的首选方法,因为其成功率合理且发病率较低。本报告描述了采用这种方法的结果。
对10例脑脊液鼻漏患者采用扩大颅下入路。选择标准包括直径大于15毫米的前颅底缺损、内镜无法到达的缺损、术前无法定位的瘘口部位以及筛板区域的多发和横行骨折。随访时间为8至23个月,平均17个月。
9例(90%)患者的鼻漏得到解决。嗅觉丧失是唯一的术后并发症,8例患者出现。
作者得出结论,扩大颅下入路处理前颅底是治疗涉及前颅底的脑脊液鼻漏的一种安全、通用且有效的手术方法。