Gatot A, Fliss D M, Zucker G, Amir A, Cohen A, Leiberman A, Reichental E
Service d'ORL et de chirurgie cervico-faciale, Hôpital Soroka, B.P. 151, Beer-Sheva, 84101. Israël.
Ann Otolaryngol Chir Cervicofac. 2000 Dec;117(6):367-373.
We reviewed the cases of 75 patients who underwent an extended subcranial approach to the anterior skull base for treatment of various tumors (35 patients), repair of craniofacial trauma injury (33 patients), or cerebrospinal fluid leakage (10 patients). Preoperative evaluation and surgical procedures were reassessed. Significant complications in the oncology group consisted of one hematoma requiring aspiration, 2 cases of transient pneumocephalus, 2 osteocutaneous fistulae and 2 epiphoras. In the trauma group, one patient died from intracerebral damage, 2 presented with transient pneumocephalus, 5 with telecanthus and 5 with enophthalmy. The most frequent late complication in all three groups was anosmia. Based on this review, we feel that this technique is a safe and effective procedure for the surgical treatment of various pathological conditions involving the anterior skull base.
我们回顾了75例接受扩大颅下入路治疗前颅底各种肿瘤（35例）、修复颅面创伤损伤（33例）或脑脊液漏（10例）的患者病例。对术前评估和手术过程进行了重新评估。肿瘤学组的重大并发症包括1例需要抽吸的血肿、2例短暂性气颅、2例骨皮瘘和2例泪溢。创伤组中，1例患者死于脑损伤，2例出现短暂性气颅，5例出现内眦距增宽，5例出现眼球内陷。所有三组中最常见的晚期并发症是嗅觉丧失。基于这项回顾，我们认为该技术是一种安全有效的手术方法，可用于治疗涉及前颅底的各种病理状况。
