The role of the vascular wall in the mechanism of control of blood coagulation and fibrinolysis on stimulation of the vagus nerve.

In experiments on 50 dogs it was found that on stimulation of the vagus nerve, tissue thromboplastin and activators of fibrinolysis are released from arterial and venous walls. The release of these factors elicits changes in the blood coagulation, with a resulting acceleration of blood coagulation and an activation of fibrinolysis.