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The p70 S6 kinase integrates nutrient and growth signals to control translational capacity.

作者信息

Avruch J, Belham C, Weng Q, Hara K, Yonezawa K

机构信息

Diabetes Unit and Medical Services, Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.

出版信息

Prog Mol Subcell Biol. 2001;26:115-54. doi: 10.1007/978-3-642-56688-2_5.

DOI:10.1007/978-3-642-56688-2_5
PMID:11575164
Abstract
摘要

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The p70 S6 kinase integrates nutrient and growth signals to control translational capacity.p70 S6激酶整合营养和生长信号以控制翻译能力。
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Control of translation by the target of rapamycin proteins.雷帕霉素蛋白靶点对翻译的调控
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TOR signalling and control of cell growth.TOR信号传导与细胞生长调控
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Target of rapamycin-dependent activation of S6 kinase is a central step in the transduction of nutritional signals during egg development in a mosquito.雷帕霉素靶蛋白依赖性激活S6激酶是蚊子卵子发育过程中营养信号转导的核心步骤。
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3-Phosphoinositide-dependent protein kinase 1 (PDK1) phosphorylates and activates the p70 S6 kinase in vivo and in vitro.3-磷酸肌醇依赖性蛋白激酶1（PDK1）在体内和体外均可磷酸化并激活p70 S6激酶。
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