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竹节样改变:原发性声带病变作为自身免疫性疾病的证据。

Bamboo node: primary vocal fold lesion as evidence of autoimmune disease.

作者信息

Murano E, Hosako-Naito Y, Tayama N, Oka T, Miyaji M, Kumada M, Niimi S

机构信息

Department of Otolaryngology, University of Tokyo, Japan.

出版信息

J Voice. 2001 Sep;15(3):441-50. doi: 10.1016/S0892-1997(01)00044-3.

Abstract

Descriptions of vocal fold lesions related to autoimmune diseases are rare in the literature, and focus mainly on rheumatoid nodules. This is the first report in which autoimmune diseases were promptly suspected by the observation of a unique white transverse submucosal lesion in the vocal fold during clinical examination. This lesion, reported only in autoimmune disease, has been called the bamboo node and its features are different from those of rheumatoid nodules. We report here on two patients who did not have a diagnosis of systemic disease before investigation of their main complaint of hoarseness. At the patients' first visit, vocal fold bamboo nodes were seen in the vocal fold and the otolaryngologist suspected the presence of an autoimmune disease. We requested clinical investigation to clarify our suspicion that there was an underlying systemic disease. After the investigation, both patients were shown to have autoimmune disease, Sjögren's syndrome and systemic lupus erythematous, respectively. This paper emphasizes the important role of the otolaryngologist in the detection of these unique lesions in the vocal folds through the conventional laryngeal methods. These methods consisted of direct observation with a rigid laryngeal endoscope and investigation of the patient's distinctive vibratory pattern by means of laryngeal stroboscopy. The method of treatment we used to obtain the best outcome in terms of voice improvement is also discussed.

摘要

关于自身免疫性疾病相关声带病变的描述在文献中很少见,且主要集中在类风湿结节。这是第一份报告,临床检查时通过观察声带中独特的白色横向黏膜下病变迅速怀疑为自身免疫性疾病。这种仅在自身免疫性疾病中出现的病变被称为竹节样结节,其特征与类风湿结节不同。我们在此报告两名患者,他们在因声音嘶哑这一主要诉求接受检查之前未被诊断出患有全身性疾病。在患者首次就诊时,声带中可见竹节样结节,耳鼻喉科医生怀疑存在自身免疫性疾病。我们要求进行临床检查以明确我们关于存在潜在全身性疾病的怀疑。检查后,两名患者分别被诊断患有自身免疫性疾病,即干燥综合征和系统性红斑狼疮。本文强调了耳鼻喉科医生通过传统喉镜检查方法在发现声带这些独特病变中的重要作用。这些方法包括使用硬质喉镜直接观察以及通过喉频闪喉镜检查患者独特的振动模式。我们还讨论了为在声音改善方面获得最佳效果而采用的治疗方法。

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