Simon A, Fleischhack G
Abteilung für pädiatrische Hämatologie und Onkologie, Zentrum für Kinderheilkunde der Universität Bonn, Germany.
Klin Padiatr. 2001 Sep;213 Suppl 1:A106-13. doi: 10.1055/s-2001-17507.
Immunocompromised patients in pediatric hematology-oncology are faced with an increased risk of nosocomial infections (NI). The incidence of NI and the contribution of certain risk factors have not sufficiently been investigated in this population. It is therefore unknown how many NI are preventable through infection control measures. The surveillance of NI in pediatric hematology-oncology departments should focus on device-associated infections (central venous catheter infection, urinary tract infection), on nosocomial pneumonia (in particular due to Aspergillus) and on infectious complications caused by Respiratory Syncytial-Virus and Rotavirus. The surveillance protocol should be based on a modified version of the Centers for Disease Control and Prevention methods (established definitions of NI can not be completely applied to pediatric oncology patients). Prospective surveillance for NI on pediatric hematology/oncology units is an indispensable tool for internal quality control. The careful evaluation of specific NI-rates permits the identification of critical control points, that may be targeted by infection control programs.
儿科血液肿瘤学中的免疫受损患者面临医院感染(NI)风险增加的问题。该人群中NI的发病率以及某些风险因素的作用尚未得到充分研究。因此,尚不清楚通过感染控制措施可预防多少NI。儿科血液肿瘤学部门对NI的监测应侧重于与设备相关的感染(中心静脉导管感染、尿路感染)、医院获得性肺炎(尤其是由曲霉菌引起的)以及由呼吸道合胞病毒和轮状病毒引起的感染并发症。监测方案应基于疾病控制和预防中心方法的修改版本(NI的既定定义不能完全应用于儿科肿瘤患者)。对儿科血液学/肿瘤学病房的NI进行前瞻性监测是内部质量控制不可或缺的工具。对特定NI发生率的仔细评估有助于确定关键控制点,而感染控制计划可针对这些控制点。