Aubert M, Blaho J A
Department of Microbiology, Box 1124, Mount Sinai School of Medicine, One Gustave L. Levy Place, New York, NY 10029-6574, USA.
Microbes Infect. 2001 Aug;3(10):859-66. doi: 10.1016/s1286-4579(01)01444-7.
Human herpes simplex virus (HSV) is cytolytic and has profound impacts on its host cells. Consequences of HSV infection include the induction of apoptosis and the concomitant synthesis of proteins which act to block this process. We review recent evidence showing how this important human pathogen modulates the fundamental cell death process.
人类单纯疱疹病毒(HSV)具有细胞溶解性,对其宿主细胞有深远影响。HSV感染的后果包括诱导细胞凋亡以及同时合成阻止这一过程的蛋白质。我们综述了近期的证据,展示了这种重要的人类病原体如何调节基本的细胞死亡过程。