采用甲吡唑和血液透析治疗儿童甲醇摄入。

Childhood methanol ingestion treated with fomepizole and hemodialysis.

作者信息

Brown M J, Shannon M W, Woolf A, Boyer E W

机构信息

Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Pediatrics. 2001 Oct;108(4):E77. doi: 10.1542/peds.108.4.e77.

DOI:10.1542/peds.108.4.e77

PMID:11581485

Abstract

Fomepizole (4-methylpyrazole; Antizol) is used increasingly in the treatment of methanol toxicity in adults. Little experience exists with this drug in the pediatric population, however. We present a case of methanol poisoning in a child in whom the use of fomepizole averted intravenous ethanol infusion and the attendant side effects of this therapy.

摘要

甲吡唑（4-甲基吡唑；安替唑）在成人甲醇中毒治疗中的应用日益广泛。然而，该药在儿科人群中的使用经验较少。我们报告一例儿童甲醇中毒病例，该病例中使用甲吡唑避免了静脉输注乙醇及其伴随的治疗副作用。