Mrochen M, Seiler T
University of Zurich, Dept. of Ophthalmology, Switzerland.
J Refract Surg. 2001 Sep-Oct;17(5):S584-7. doi: 10.3928/1081-597X-20010901-15.
The aim of this work was to clarify the influence of the effective illumination area and possible reflection losses that occur during laser-tissue interaction on the modeling of profiles for customized corneal ablation, such as wavefront-guided treatments.
The changes of the ablation depth per laser pulse due to the projection of a laser spot onto the corneal front surface and reflection losses at the air-tissue interface were calculated.
Moving with a scanning-spot from the center of the cornea toward the limbus resulted in an increase of the effective illumination area and reflection losses, which led to a decrease in the ablation depth per laser pulse. The decrease of the ablation depth was strongly related to the initial radiant exposure and the corneal curvature radius.
The corneal front surface must be taken into consideration for ablation profile calculations, especially in customized treatments, due to the strong dependence of the ablation depth on the corneal curvature.
本研究旨在阐明有效照射面积以及激光与组织相互作用期间发生的可能反射损失对定制角膜消融（如波前引导治疗）轮廓建模的影响。
计算了由于激光光斑投射到角膜前表面以及气-组织界面处的反射损失导致的每个激光脉冲消融深度的变化。
随着扫描光斑从角膜中心向角膜缘移动，有效照射面积和反射损失增加，导致每个激光脉冲的消融深度降低。消融深度的降低与初始辐射暴露和角膜曲率半径密切相关。
由于消融深度强烈依赖于角膜曲率，因此在计算消融轮廓时必须考虑角膜前表面，尤其是在定制治疗中。
