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冠状动脉旁路移植术的结局与成本:三级医疗中心八旬老人与七旬老人的比较

Outcomes and costs of coronary artery bypass grafting: comparison between octogenarians and septuagenarians at a tertiary care centre.

作者信息

Smith K M, Lamy A, Arthur H M, Gafni A, Kent R

机构信息

CADENCE Research Group, Hamilton Health Sciences Corporation-General Division, Hamilton, Ont.

出版信息

CMAJ. 2001 Sep 18;165(6):759-64.

Abstract

BACKGROUND

Decision-making related to coronary artery bypass grafting (CABG) in elderly patients is hampered by inadequate outcome data. We compared the clinical outcomes of octogenarians with those of septuagenarians who underwent CABG. Our secondary objective was to compare the costs associated with CABG in these groups.

METHODS

We conducted a retrospective database review of patients 70 years of age and older who had undergone CABG at a regional cardiac surgical centre in Hamilton, Ont., between July 1, 1997, and Apr. 30, 2000. A total of 1034 patients were divided into 3 age groups: young septuagenarians (aged 70-74 years), old septuagenarians (aged 75-79) and those 80 and older. Costs were determined in a subset of 773 patients with the use of a case-costing system for cardiac surgery developed at our institution.

RESULTS

The 3 groups were similar with respect to sex distribution and preoperative risk factors. Urgency scores at referral differed significantly between the groups, with the young septuagenarians demonstrating the lowest risk (mean score [and standard deviation] 4.48 [1.3] in that group, 4.28 [1.4] in the old septuagenarian group and 4.11 [1.2] in the octogenarian group). The rates of all complications combined were similar between the 3 groups (27.1%, 28.1% and 29.6% in the young and old septuagenarian groups and the octogenarian group respectively). There were no significant differences between the 3 groups in the mean number of grafts per patient (3.0, 3.1 and 3.0 respectively), the rate of postoperative death (3.3%, 5.7% and 4.2%), the mean length of stay (11.7, 13.4 and 12.6 days) or the incidence of postoperative myocardial infarction (4.5%, 3.4% and 4.2%). The total cost of CABG per patient did not differ significantly between the 3 groups.

INTERPRETATION

Given that patients who are accepted for CABG represent a selected population, our findings suggest that, with careful triage, CABG in octogenarians is as safe as, and no more costly than, CABG in septuagenarians.

摘要

背景

老年患者冠状动脉旁路移植术(CABG)相关的决策因结局数据不足而受到阻碍。我们比较了接受CABG的八旬老人与七旬老人的临床结局。我们的次要目标是比较这些组中与CABG相关的费用。

方法

我们对1997年7月1日至2000年4月30日期间在安大略省汉密尔顿一家地区心脏外科中心接受CABG的70岁及以上患者进行了回顾性数据库审查。总共1034名患者被分为3个年龄组:年轻的七旬老人(70 - 74岁)、年老的七旬老人(75 - 79岁)和80岁及以上的老人。在773名患者的子集中,使用我们机构开发的心脏手术病例成本核算系统确定费用。

结果

3组在性别分布和术前危险因素方面相似。转诊时的紧急程度评分在各组之间有显著差异,年轻的七旬老人风险最低(该组平均评分[及标准差]为4.48[1.3],年老的七旬老人组为4.28[1.4],八旬老人组为4.11[1.2])。3组所有并发症的总发生率相似(年轻和年老的七旬老人组以及八旬老人组分别为27.1%、28.1%和29.6%)。3组在每位患者的平均移植血管数量(分别为3.0、3.1和3.0)、术后死亡率(3.3%、5.7%和4.2%)、平均住院时间(11.7、13.4和12.6天)或术后心肌梗死发生率(4.5%、3.4%和4.2%)方面没有显著差异。3组中每位患者CABG的总成本没有显著差异。

解读

鉴于接受CABG的患者是经过挑选的人群,我们的研究结果表明,经过仔细筛选,八旬老人进行CABG与七旬老人进行CABG一样安全,且费用不会更高。

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