Lamy Andre, Wang Xiaoyin, Farrokhyar Forough, Kent Rosanne
Department of Surgery, McMaster University, Hamilton, Ontario, Canada.
Can J Cardiol. 2006 Jun;22(8):699-704. doi: 10.1016/s0828-282x(06)70939-4.
Evidence suggests that off-pump coronary artery bypass graft surgery (CABG) is as safe and effective as on-pump CABG, and the cost of initial hospitalization for off-pump CABG is less expensive than on-pump CABG. However, it is uncertain whether the cost savings are sustained over a longer period of time.
To assess in-hospital and one-year direct medical costs of off-pump CABG versus on-pump CABG in the context of the Canadian health care system.
From March 2001 to December 2002, 1657 consecutive patients enrolled in the Canadian Off-Pump CABG Registry were compared with 1693 consecutive on-pump patients from Hamilton Health Sciences CABG database. At one year, patients of both groups were followed by telephone interview. An economic analysis was conducted from the perspective of the Ontario Ministry of Health and Long-Term Care, and the data analysis was based on propensity score-matched registry patients (1233 pairs) to ensure the comparability of the two study groups. Clinical event and resource use information was collected from all patients. Unit costs from the Hamilton Health Sciences case-costing system were used to estimate hospital costs; all costs were reported in 2003 Canadian dollars. Sensitivity analyses were performed to account for uncertainties. The cost of initial hospitalization for off-pump CABG was significantly less than on-pump CABG (11,744 dollars versus 13,720 dollars, P < 0.001). Although follow-up costs were similar between the groups, the one-year total cost per patient for off-pump CABG remained significantly less than on-pump CABG (12,063 dollars versus 14,141 dollars, P < 0.001).
Off-pump CABG offers significant savings during initial hospitalization that are also sustained after one year.
有证据表明,非体外循环冠状动脉旁路移植术(CABG)与体外循环CABG一样安全有效,且非体外循环CABG的首次住院费用低于体外循环CABG。然而,尚不确定这些成本节约是否能在更长时间内持续。
在加拿大医疗保健系统背景下,评估非体外循环CABG与体外循环CABG的住院期间及一年直接医疗成本。
2001年3月至2002年12月,将加拿大非体外循环CABG注册研究中连续纳入的1657例患者与汉密尔顿健康科学中心CABG数据库中连续的1693例体外循环患者进行比较。一年时,通过电话访谈对两组患者进行随访。从安大略省卫生和长期护理部的角度进行经济分析,数据分析基于倾向评分匹配的注册患者(1233对)以确保两个研究组具有可比性。收集所有患者的临床事件和资源使用信息。使用汉密尔顿健康科学中心病例成本核算系统的单位成本来估算医院成本;所有成本均以2003年加元报告。进行敏感性分析以考虑不确定性。非体外循环CABG的首次住院成本显著低于体外循环CABG(11,744加元对13,720加元,P < 0.001)。尽管两组的随访成本相似,但非体外循环CABG患者的一年总成本仍显著低于体外循环CABG(12,063加元对14,141加元,P < 0.001)。
非体外循环CABG在首次住院期间可显著节省成本,且一年后仍能持续。