Werner T
Nat Genet. 2001 Oct;29(2):105-6. doi: 10.1038/ng1001-105.
The availability of the complete genomic sequence of yeast now enables elucidation of molecular mechanisms governing gene expression patterns. New results from the yeast genome and recent advances in predicting and finding human promoters support the use of similar combinatorial approaches to study genome-wide transcriptional regulation in humans.
酵母完整基因组序列的可得性,如今使得阐明调控基因表达模式的分子机制成为可能。来自酵母基因组的新成果以及在预测和寻找人类启动子方面的最新进展,支持采用类似的组合方法来研究人类全基因组范围的转录调控。